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3ion

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Revision as of 06:28, 24 March 2010

Image:3ion.png

Template:STRUCTURE 3ion

PDK1 in complex with Compound 8h

Template:ABSTRACT PUBMED 20074837

About this Structure

3ION is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Nittoli T, Dushin RG, Ingalls C, Cheung K, Floyd MB, Fraser H, Olland A, Hu Y, Grosu G, Han X, Arndt K, Guo B, Wissner A. The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-y lamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1). Eur J Med Chem. 2010 Apr;45(4):1379-86. Epub 2009 Dec 28. PMID:20074837 doi:10.1016/j.ejmech.2009.12.036

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