Apurinic-Apyrimidinic Endonuclease

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=Introduction=
=Introduction=
APE1 is an endonuclease <ref>Barnes,T</ref>.
APE1 is an endonuclease <ref>Barnes,T</ref>.
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[[Image:APE!.png|250 px|right]]
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[[Image:APE!.png|250 px|right]]
 
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APE1 works in the base excision repair pathway
APE1 works in the base excision repair pathway
[[Image:BERpath.png|250 px|right]]
[[Image:BERpath.png|250 px|right]]
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<applet load='1de8' size='300' color='white' frame='true' align='left' caption='APE interacting with DNA'/>
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<applet load='1de8' size='300' color='white' frame='true' align='left' caption='APE interacting with DNA'/>
 
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==APE1 AND RNA==
==APE1 AND RNA==
APE1 HAS BEEN SHOWN TO CLEAVE C-MYC MRNA
APE1 HAS BEEN SHOWN TO CLEAVE C-MYC MRNA
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[[Image:APEmech.png|500 px|right]]
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[[Image:APEmech.png|500 px|right]]
 

Revision as of 02:39, 25 March 2010

Contents

Apurinic/apyrimidinic endonuclease-1 (APE1)

Introduction

APE1 is an endonuclease [1].

Image:APE!.png















APE1'S INTERACTIONS WITH DNA

APE1 works in the base excision repair pathway

Image:BERpath.png

APE interacting with DNA

Drag the structure with the mouse to rotate




















APE1 AND RNA

APE1 HAS BEEN SHOWN TO CLEAVE C-MYC MRNA

Image:APEmech.png


















References

  1. ↑ Barnes,T
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