Apurinic-Apyrimidinic Endonuclease

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Revision as of 03:56, 25 March 2010

Contents

APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1)

INTRODUCTION

APE1 is an endonuclease [1].















STRUCTURE AND FUNCTION

APE1 works in the base excision repair pathway

APE interacting with DNA

Drag the structure with the mouse to rotate



















POPULATION VARIENTS

APE1 HAS BEEN SHOWN TO CLEAVE C-MYC MRNA



























REFERENCES

  1. Barnes,T
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