1yy9
From Proteopedia
(Difference between revisions)
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{{ABSTRACT_PUBMED_15837620}} | {{ABSTRACT_PUBMED_15837620}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]], Nonsmall cell lung cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=131550 131550]] | ||
==About this Structure== | ==About this Structure== | ||
| - | 1YY9 is a 3 chains structure | + | 1YY9 is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus,_homo_sapiens Mus musculus, homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YY9 OCA]. |
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:15837620</ref><references group="xtra"/> | <ref group="xtra">PMID:15837620</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Mus musculus | + | [[Category: Mus musculus, homo sapiens]] |
| - | [[Category: | + | [[Category: Receptor protein-tyrosine kinase]] |
[[Category: Ferguson, K M.]] | [[Category: Ferguson, K M.]] | ||
[[Category: Jeffrey, P D.]] | [[Category: Jeffrey, P D.]] | ||
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[[Category: Fab fragment]] | [[Category: Fab fragment]] | ||
[[Category: Glycoprotein]] | [[Category: Glycoprotein]] | ||
| + | [[Category: Immune system-transferase complex]] | ||
[[Category: Tyrosine kinase]] | [[Category: Tyrosine kinase]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 31 12:57:37 2010'' |
Revision as of 09:57, 31 March 2010
Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225
Template:ABSTRACT PUBMED 15837620
About this Structure
1YY9 is a 3 chains structure with sequences from Homo sapiens and Mus musculus, homo sapiens. Full crystallographic information is available from OCA.
Reference
- Li S, Schmitz KR, Jeffrey PD, Wiltzius JJ, Kussie P, Ferguson KM. Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell. 2005 Apr;7(4):301-11. PMID:15837620 doi:10.1016/j.ccr.2005.03.003
Page seeded by OCA on Wed Mar 31 12:57:37 2010
Categories: Homo sapiens | Mus musculus, homo sapiens | Receptor protein-tyrosine kinase | Ferguson, K M. | Jeffrey, P D. | Kussie, P. | Li, S. | Schmitz, K R. | Wiltzius, J J.W. | Antigen:antibody complex | Antitumor | Cell surface receptor | Drug | Fab fragment | Glycoprotein | Immune system-transferase complex | Tyrosine kinase
