Calcium-free Calmodulin

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<table style="background-color:#fccfc0" cellpadding="8" width="95%" border="0"><tr><td>Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. [[User:Andrea Gorrell|Andrea Chris Truscott
<table style="background-color:#fccfc0" cellpadding="8" width="95%" border="0"><tr><td>Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. [[User:Andrea Gorrell|Andrea Chris Truscott
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===Calcium-free Calmodulin===
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== '''Calcium-free Calmodulin''' ==
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==='''General Information'''===
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----
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Calmodulin is a molecule that has been studied extensively in its functions within the cell, and has an important role in relaying Ca2+ signals within the cytosol. <ref name="1TSON">Hoeflich, K.P., & Ikura, M.. Calmodulin in action: diversity in target recognition and activation mechanisms, Cell. 2002 108:739-742</ref> I does this by binding to Ca2+, undergoing a conformational change, and may interact with various proteins within the cell. <ref name=”1TSON”/> <ref name=”2TSON”/>Babu YS, Bugg CE, Cook WJ. Structure of calmodulin refined at 2.2 A resolution. J Mol Biol. 1988 Nov 5;204(1):191-204. PMID:3145979</ref> <ref name="3TSON">Kuboniwa H, Tjandra N, Grzesiek S, Ren H, Klee CB, Bax A. Solution structure of calcium-free calmodulin. Nat Struct Biol. 1995 Sep;2(9):768-76. PMID:7552748</ref>
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[[Image:1cfc.png|left|200px]]
{{STRUCTURE_1cfc| PDB=1cfc | SCENE=Sandbox_190/1cfc/1 }}
{{STRUCTURE_1cfc| PDB=1cfc | SCENE=Sandbox_190/1cfc/1 }}
<scene name='Sandbox_190/1cfc/1'>TextToBeDisplayed</scene>
<scene name='Sandbox_190/1cfc/1'>TextToBeDisplayed</scene>
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==References==
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<references/>
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<ref group="xtra">PMID:3145979</ref><references group="xtra"/>
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<ref group="xtra">PMID:7552748</ref><references group="xtra"/>

Revision as of 04:55, 1 April 2010

Please do NOT make changes to this Sandbox until after April 23, 2010. Sandboxes 151-200 are reserved until then for use by the Chemistry 307 class at UNBC taught by Prof. [[User:Andrea Gorrell|Andrea Chris Truscott

Calcium-free Calmodulin

General Information

Calmodulin is a molecule that has been studied extensively in its functions within the cell, and has an important role in relaying Ca2+ signals within the cytosol. [1] I does this by binding to Ca2+, undergoing a conformational change, and may interact with various proteins within the cell. Cite error: Invalid <ref> tag; refs with no content must have a name Cite error: Invalid <ref> tag; refs with no content must have a nameBabu YS, Bugg CE, Cook WJ. Structure of calmodulin refined at 2.2 A resolution. J Mol Biol. 1988 Nov 5;204(1):191-204. PMID:3145979</ref> [2]


Image:1cfc.png

PDB ID 1cfc

Drag the structure with the mouse to rotate
1cfc, 25 NMR models ()
Related: 1cfd
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



References

  1. ↑ Hoeflich, K.P., & Ikura, M.. Calmodulin in action: diversity in target recognition and activation mechanisms, Cell. 2002 108:739-742
  2. ↑ Kuboniwa H, Tjandra N, Grzesiek S, Ren H, Klee CB, Bax A. Solution structure of calcium-free calmodulin. Nat Struct Biol. 1995 Sep;2(9):768-76. PMID:7552748
  • Babu YS, Bugg CE, Cook WJ. Structure of calmodulin refined at 2.2 A resolution. J Mol Biol. 1988 Nov 5;204(1):191-204. PMID:3145979
  • Kuboniwa H, Tjandra N, Grzesiek S, Ren H, Klee CB, Bax A. Solution structure of calcium-free calmodulin. Nat Struct Biol. 1995 Sep;2(9):768-76. PMID:7552748
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