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3is9
From Proteopedia
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| + | {{STRUCTURE_3is9| PDB=3is9 | SCENE= }} | ||
| - | + | ===Crystal structure of the HIV-1 reverse transcriptase (RT) in complex with the alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate).=== | |
| - | Description: Crystal structure of the HIV-1 reverse transcriptase (RT) in complex with the alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate). | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed | + | <!-- |
| + | The line below this paragraph, {{ABSTRACT_PUBMED_19775161}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 19775161 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_19775161}} | ||
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| + | ==About this Structure== | ||
| + | 3IS9 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_type_1_bh10 Human immunodeficiency virus type 1 bh10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IS9 OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:19775161</ref><references group="xtra"/> | ||
| + | [[Category: Human immunodeficiency virus type 1 bh10]] | ||
| + | [[Category: Arnold, E.]] | ||
| + | [[Category: Bauman, J D.]] | ||
| + | [[Category: Das, K.]] | ||
| + | [[Category: Ho, W C.]] | ||
| + | [[Category: Adam]] | ||
| + | [[Category: Aid]] | ||
| + | [[Category: Aspartyl protease]] | ||
| + | [[Category: Cell membrane]] | ||
| + | [[Category: Cytoplasm]] | ||
| + | [[Category: Dna integration]] | ||
| + | [[Category: Dna recombination]] | ||
| + | [[Category: Dna-directed dna polymerase]] | ||
| + | [[Category: Endonuclease]] | ||
| + | [[Category: Hiv]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Lipoprotein]] | ||
| + | [[Category: Membrane]] | ||
| + | [[Category: Metal-binding]] | ||
| + | [[Category: Multifunctional enzyme]] | ||
| + | [[Category: Myristate]] | ||
| + | [[Category: Nnrti]] | ||
| + | [[Category: Nonnucleoside inhibitor]] | ||
| + | [[Category: Nuclease]] | ||
| + | [[Category: Nucleotidyltransferase]] | ||
| + | [[Category: Nucleus]] | ||
| + | [[Category: P51/p66]] | ||
| + | [[Category: Phosphoprotein]] | ||
| + | [[Category: Protease]] | ||
| + | [[Category: Rna-binding]] | ||
| + | [[Category: Rna-directed dna polymerase]] | ||
| + | [[Category: Transferase]] | ||
| + | [[Category: Transferase-hydrolase complex]] | ||
| + | [[Category: Viral nucleoprotein]] | ||
| + | [[Category: Virion]] | ||
| + | [[Category: Zinc]] | ||
| + | [[Category: Zinc-finger]] | ||
| + | |||
| + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 7 10:40:22 2010'' | ||
Revision as of 07:40, 7 April 2010
Crystal structure of the HIV-1 reverse transcriptase (RT) in complex with the alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate).
Template:ABSTRACT PUBMED 19775161
About this Structure
3IS9 is a 2 chains structure with sequences from Human immunodeficiency virus type 1 bh10. Full crystallographic information is available from OCA.
Reference
- Cullen MD, Ho WC, Bauman JD, Das K, Arnold E, Hartman TL, Watson KM, Buckheit RW, Pannecouque C, De Clercq E, Cushman M. Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase. J Med Chem. 2009 Oct 22;52(20):6467-73. PMID:19775161 doi:10.1021/jm901167t
Page seeded by OCA on Wed Apr 7 10:40:22 2010
Categories: Human immunodeficiency virus type 1 bh10 | Arnold, E. | Bauman, J D. | Das, K. | Ho, W C. | Adam | Aid | Aspartyl protease | Cell membrane | Cytoplasm | Dna integration | Dna recombination | Dna-directed dna polymerase | Endonuclease | Hiv | Hydrolase | Lipoprotein | Membrane | Metal-binding | Multifunctional enzyme | Myristate | Nnrti | Nonnucleoside inhibitor | Nuclease | Nucleotidyltransferase | Nucleus | P51/p66 | Phosphoprotein | Protease | Rna-binding | Rna-directed dna polymerase | Transferase | Transferase-hydrolase complex | Viral nucleoprotein | Virion | Zinc | Zinc-finger
