1hjz
From Proteopedia
Line 1: | Line 1: | ||
- | [[Image:1hjz. | + | [[Image:1hjz.jpg|left|200px]]<br /><applet load="1hjz" size="450" color="white" frame="true" align="right" spinBox="true" |
- | <applet load="1hjz" size="450" color="white" frame="true" align="right" spinBox="true" | + | |
caption="1hjz, resolution 1.7Å" /> | caption="1hjz, resolution 1.7Å" /> | ||
'''CRYSTAL STRUCTURE OF AF1521 PROTEIN CONTAINING A MACROH2A DOMAIN'''<br /> | '''CRYSTAL STRUCTURE OF AF1521 PROTEIN CONTAINING A MACROH2A DOMAIN'''<br /> | ||
Line 8: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
- | 1HJZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus] with MES as [http://en.wikipedia.org/wiki/ligand ligand]. | + | 1HJZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Archaeoglobus_fulgidus Archaeoglobus fulgidus] with MES as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Mes Binding Site For Chain B'>AC1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1HJZ OCA]. |
==Reference== | ==Reference== | ||
Line 23: | Line 22: | ||
[[Category: histone macroh2a]] | [[Category: histone macroh2a]] | ||
- | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 16:28:16 2007'' |
Revision as of 14:18, 18 December 2007
|
CRYSTAL STRUCTURE OF AF1521 PROTEIN CONTAINING A MACROH2A DOMAIN
Overview
MacroH2A is an unusual histone H2A variant that has an extensive, C-terminal tail that comprises approximately two thirds of the protein., The C-terminal non-histone domain of macroH2A is also found in a number of, other proteins and has been termed the macro domain. Here we report the, crystal structure to 1.7A of AF1521, a protein consisting of a stand-alone, macro domain from Archaeoglobus fulgidus. The structure has a mixed, alpha/beta fold that closely resembles the N-terminal DNA binding domain, of the Escherichia coli leucine aminopeptidase PepA. The structure also, shows some similarity to members of the P-loop family of nucleotide, hydrolases.
About this Structure
1HJZ is a Single protein structure of sequence from Archaeoglobus fulgidus with MES as ligand. Known structural/functional Site: . Full crystallographic information is available from OCA.
Reference
The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A., Allen MD, Buckle AM, Cordell SC, Lowe J, Bycroft M, J Mol Biol. 2003 Jul 11;330(3):503-11. PMID:12842467
Page seeded by OCA on Tue Dec 18 16:28:16 2007