3jwz

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'''Unreleased structure'''
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{{Seed}}
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[[Image:3jwz.jpg|left|200px]]
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The entry 3jwz is ON HOLD until Paper Publication
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{{STRUCTURE_3jwz| PDB=3jwz | SCENE= }}
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Authors: Delker, S.L., Li, H., Poulos, T.L.
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===Structure of endothelial nitric oxide synthase heme domain complexed with N1-[(3' S,4' R)-4'-((6"-amino-4"-methylpyridin-2"-yl)methyl)pyrrolidin-3'-yl]-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride===
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Description: Structure of endothelial nitric oxide synthase heme domain complexed with N1-[(3' S,4' R)-4'-((6"-amino-4"-methylpyridin-2"-yl)methyl)pyrrolidin-3'-yl]-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 7 13:44:01 2009''
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{{ABSTRACT_PUBMED_20337441}}
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==About this Structure==
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3JWZ is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JWZ OCA].
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==Reference==
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<ref group="xtra">PMID:20337441</ref><references group="xtra"/>
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[[Category: Bos taurus]]
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[[Category: Nitric-oxide synthase]]
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[[Category: Delker, S L.]]
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[[Category: Li, H.]]
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[[Category: Poulos, T L.]]
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[[Category: Heme enzyme]]
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[[Category: Oxidoreductase]]
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[[Category: Substrate inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 5 12:01:04 2010''

Revision as of 09:01, 5 May 2010

Image:3jwz.jpg

Template:STRUCTURE 3jwz

Structure of endothelial nitric oxide synthase heme domain complexed with N1-[(3' S,4' R)-4'-((6"-amino-4"-methylpyridin-2"-yl)methyl)pyrrolidin-3'-yl]-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride

Template:ABSTRACT PUBMED 20337441

About this Structure

3JWZ is a 2 chains structure with sequences from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Delker SL, Ji H, Li H, Jamal J, Fang J, Xue F, Silverman RB, Poulos TL. Unexpected binding modes of nitric oxide synthase inhibitors effective in the prevention of a cerebral palsy phenotype in an animal model. J Am Chem Soc. 2010 Apr 21;132(15):5437-42. PMID:20337441 doi:10.1021/ja910228a

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