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3mjw

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Revision as of 04:13, 16 June 2010

Image:3mjw.png

Template:STRUCTURE 3mjw

PI3 Kinase gamma with a benzofuranone inhibitor

Template:ABSTRACT PUBMED 20483602

About this Structure

3MJW is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Zhang N, Ayral-Kaloustian S, Anderson JT, Nguyen T, Das S, Venkatesan AM, Brooijmans N, Lucas J, Yu K, Hollander I, Mallon R. 5-ureidobenzofuranone indoles as potent and efficacious inhibitors of PI3 kinase-alpha and mTOR for the treatment of breast cancer. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3526-9. Epub 2010 May 17. PMID:20483602 doi:10.1016/j.bmcl.2010.04.139

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