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3lj6

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Revision as of 04:29, 16 June 2010

Image:3lj6.png

Template:STRUCTURE 3lj6

3D-CRYSTAL STRUCTURE OF HUMANIZED-RAT FATTY ACID AMIDE HYDROLASE (FAAH) CONJUGATED WITH THE DRUG-LIKE UREA INHIBITOR PF-3845 at 2.42A RESOLUTION

Template:ABSTRACT PUBMED 20493882

About this Structure

3LJ6 is a 2 chains structure with sequences from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Mileni M, Kamtekar S, Wood DC, Benson TE, Cravatt BF, Stevens RC. Crystal structure of fatty acid amide hydrolase bound to the carbamate inhibitor URB597: discovery of a deacylating water molecule and insight into enzyme inactivation. J Mol Biol. 2010 Jul 23;400(4):743-54. Epub 2010 May 21. PMID:20493882 doi:10.1016/j.jmb.2010.05.034

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