This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Severin
From Proteopedia
| Line 2: | Line 2: | ||
{{STRUCTURE_3fg6| PDB=3fg6 | SCENE=Severin/Cv/4 |CAPTION=Severin, [[3fg6]] }} | {{STRUCTURE_3fg6| PDB=3fg6 | SCENE=Severin/Cv/4 |CAPTION=Severin, [[3fg6]] }} | ||
| - | [[Severin]] is a calcium-activated protein which binds actin. The images at the top and at the right correspond to one representative | + | [[Severin]] is a calcium-activated protein which binds actin. The images at the top and at the right correspond to one representative severin structure, ''i.e.'' the human severin ([[3fg6]]). It nucleates actin assembly, severes F-actin and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. It is named Adseverin and Scinderin as well. The image at the right is the severin with <scene name='Severin/Cv/5'>calcium ions</scene> (<font color='lime'><b>colored lime</b></font>). |
== 3D Structures of Severin == | == 3D Structures of Severin == | ||
Revision as of 10:27, 2 September 2010
Severin is a calcium-activated protein which binds actin. The images at the top and at the right correspond to one representative severin structure, i.e. the human severin (3fg6). It nucleates actin assembly, severes F-actin and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. It is named Adseverin and Scinderin as well. The image at the right is the severin with (colored lime).
3D Structures of Severin
3fg6 – Adseverin C-terminal – human
1svy – Severin domain 2 – Dictyostelium discoideum
1svq - Severin domain 2 - Dictyostelium discoideum, NMR
