3og7

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(New page: '''Unreleased structure''' The entry 3og7 is ON HOLD Authors: Zhang, Y., Zhang, K.Y., Zhang, C. Description: B-Raf Kinase V600E oncogenic mutant in complex with PLX4032 ''Page seeded ...)
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'''Unreleased structure'''
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{{Seed}}
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[[Image:3og7.jpg|left|200px]]
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The entry 3og7 is ON HOLD
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{{STRUCTURE_3og7| PDB=3og7 | SCENE= }}
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Authors: Zhang, Y., Zhang, K.Y., Zhang, C.
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===B-Raf Kinase V600E oncogenic mutant in complex with PLX4032===
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Description: B-Raf Kinase V600E oncogenic mutant in complex with PLX4032
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 08:39:31 2010''
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{{ABSTRACT_PUBMED_20823850}}
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==About this Structure==
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3OG7 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OG7 OCA].
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==Reference==
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<ref group="xtra">PMID:20823850</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Zhang, C.]]
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[[Category: Zhang, K Y.]]
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[[Category: Zhang, Y.]]
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[[Category: B-raf]]
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[[Category: Braf]]
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[[Category: Kinase]]
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[[Category: Proto-oncogene]]
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[[Category: Transferase]]
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[[Category: V600e]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:49:16 2010''

Revision as of 11:40, 22 September 2010

Template:STRUCTURE 3og7

B-Raf Kinase V600E oncogenic mutant in complex with PLX4032

Template:ABSTRACT PUBMED 20823850

About this Structure

3OG7 is a 2 chains structure with sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bollag G, Hirth P, Tsai J, Zhang J, Ibrahim PN, Cho H, Spevak W, Zhang C, Zhang Y, Habets G, Burton EA, Wong B, Tsang G, West BL, Powell B, Shellooe R, Marimuthu A, Nguyen H, Zhang KY, Artis DR, Schlessinger J, Su F, Higgins B, Iyer R, D'Andrea K, Koehler A, Stumm M, Lin PS, Lee RJ, Grippo J, Puzanov I, Kim KB, Ribas A, McArthur GA, Sosman JA, Chapman PB, Flaherty KT, Xu X, Nathanson KL, Nolop K. Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma. Nature. 2010 Sep 7. PMID:20823850 doi:10.1038/nature09454

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