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Sandbox c16
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Estructura acetilcolinesterasa | Estructura acetilcolinesterasa | ||
| - | <Structure load='1ACJ' size=' | + | <Structure load='1ACJ' size='300' frame='true' align='right' caption='acelit colinesterasa' /> |
1ACJ shows the crystal structure of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine. | 1ACJ shows the crystal structure of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine. | ||
Tacrine is a parasympathomimetic and a centrally acting cholinesterase inhibitor. | Tacrine is a parasympathomimetic and a centrally acting cholinesterase inhibitor. | ||
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It was the first centrally-acting cholinesterase inhibitor approved for the treatment of Alzheimer's disease. | It was the first centrally-acting cholinesterase inhibitor approved for the treatment of Alzheimer's disease. | ||
| - | + | <scene name='Sandbox_c16/Modificacion_2/1'>Tacrine</scene> ring is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 (<scene name='Sandbox_c16/Modificacion_1/1'>W84 and F330</scene> ). | |
| + | <references/> | ||
| - | Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding | + | Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding <ref>PMDI 8415649</ref> |
| - | [http://www.pubmed.com publicaciones medicas] | + | [http://www.pubmed.com publicaciones medicas] <references/> |
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| + | escena copiada del señor <applet load='' size='300' frame='true' align='right' caption='' scene='User:Jaime_Prilusky/How_do_we_get_the_oxygen_we_breathe/1hho_bio/1'/> | ||
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| + | <scene name='User:Jaime_Prilusky/How_do_we_get_the_oxygen_we_breathe/1hho_bio/4'>four</scene> identical gray, red, blue and orange colored, made-of-balls elements. Let's take a closer look to <scene name='User:Jaime_Prilusky/How_do_we_get_the_oxygen_we_breathe/1hho_bio/6'>one</scene> | ||
Current revision
Estructura acetilcolinesterasa
|
1ACJ shows the crystal structure of Torpedo californica acetylcholinesterase (TcAChE) complexed with tacrine. Tacrine is a parasympathomimetic and a centrally acting cholinesterase inhibitor.
It was the first centrally-acting cholinesterase inhibitor approved for the treatment of Alzheimer's disease.
ring is stacked between the aromatic rings of tryptophan 84 and phenylalanine 330 ( ).
Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding [1]
- ↑ PMDI 8415649
|
identical gray, red, blue and orange colored, made-of-balls elements. Let's take a closer look to
