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ABC transporter
From Proteopedia
(New page: '''A'''TP '''B'''inding '''C'''assette (ABC) '''Transporters''' are ATP-dependent membrane proteins predominantly expressed in excretory organs, such as the liver, intestine, blood-bra...) |
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| - | '''A'''TP '''B'''inding '''C'''assette (ABC) '''[[Transporters]]''' are ATP-dependent membrane proteins predominantly expressed in excretory organs, such as the liver, intestine, blood-brain barrier, blood-testes barrier, placenta, and kidney<ref name="Kidney"/>. | + | '''A'''TP '''B'''inding '''C'''assette (ABC) '''[[Transporters]]''' are ATP-dependent membrane proteins predominantly expressed in excretory organs, such as the liver, intestine, blood-brain barrier, blood-testes barrier, placenta, and kidney<ref name="Kidney"/>. For instance, there are 28 in Saccharomyces,58 in Caenorhabditis, 51 in Drosophila,129 in Arabadopsis,and the 69 ABC transporters in E. coli account for almost 5% of its genomic coding capacity<ref name="EColi"/>. |
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refs= | refs= | ||
<ref name="Kidney">[http://jpet.aspetjournals.org/content/328/1/3 Huls et al. The Role of ATP Binding Cassette Transporters in Tissue Defense and Organ Regeneration. Journal of Pharmacology and Experimental Therapeutics, 2008; 328 (1)]</ref> | <ref name="Kidney">[http://jpet.aspetjournals.org/content/328/1/3 Huls et al. The Role of ATP Binding Cassette Transporters in Tissue Defense and Organ Regeneration. Journal of Pharmacology and Experimental Therapeutics, 2008; 328 (1)]</ref> | ||
| + | <ref name="EColi">[http://cel.isiknowledge.com/InboundService.do?product=CEL&action=retrieve&SrcApp=Highwire&UT=000073122300002&SID=4Bba9dOeogjJfpPPHmP&Init=Yes&SrcAuth=Highwire&mode=FullRecord&customersID=Highwire LintonKJ, Higgins CF. The Escherichia coli ATP-binding cassette (ABC) proteins. Mol Microbiol 28: 5–13, 1998]</ref> | ||
}} | }} | ||
Revision as of 16:34, 2 December 2010
ATP Binding Cassette (ABC) Transporters are ATP-dependent membrane proteins predominantly expressed in excretory organs, such as the liver, intestine, blood-brain barrier, blood-testes barrier, placenta, and kidney[1]. For instance, there are 28 in Saccharomyces,58 in Caenorhabditis, 51 in Drosophila,129 in Arabadopsis,and the 69 ABC transporters in E. coli account for almost 5% of its genomic coding capacity[2].
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| 3cin, resolution 1.70Å () | |||||||||
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| Ligands: | , , | ||||||||
| Gene: | TM1419, TM_1419 (Thermotoga maritima MSB8) | ||||||||
| Activity: | Inositol-3-phosphate synthase, with EC number 5.5.1.4 | ||||||||
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| Resources: | FirstGlance, OCA, RCSB, PDBsum, TOPSAN | ||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||
- References
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