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3c6u

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Revision as of 09:30, 26 December 2010

Image:3c6u.png

Template:STRUCTURE 3c6u

Contents

Crystal Structure of HIV Reverse Transcriptase in complex with inhibitor 22

Template:ABSTRACT PUBMED 18396399

About this Structure

3c6u is a 2 chain structure of Reverse transcriptase with sequence from Hiv-1 m:b_hxb2r. Full crystallographic information is available from OCA.

See Also

Reference

  • Tucker TJ, Saggar S, Sisko JT, Tynebor RM, Williams TM, Felock PJ, Flynn JA, Lai MT, Liang Y, McGaughey G, Liu M, Miller M, Moyer G, Munshi V, Perlow-Poehnelt R, Prasad S, Sanchez R, Torrent M, Vacca JP, Wan BL, Yan Y. The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations. Bioorg Med Chem Lett. 2008 May 1;18(9):2959-66. Epub 2008 Mar 25. PMID:18396399 doi:10.1016/j.bmcl.2008.03.064

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OCA

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