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2an5
From Proteopedia
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[[Image:2an5.png|left|200px]] | [[Image:2an5.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_16363801}} | {{ABSTRACT_PUBMED_16363801}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Hypertension, essential, 145500 (1) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=171190 171190]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2an5]] is a 2 chain structure of [[Phenylethanolamine N-methyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN5 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Phenylethanolamine N-methyltransferase]] | ||
==Reference== | ==Reference== | ||
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[[Category: Methyltransferase]] | [[Category: Methyltransferase]] | ||
[[Category: S-adenosyl-l-methionine]] | [[Category: S-adenosyl-l-methionine]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:14:37 2009'' | ||
Revision as of 20:30, 26 December 2010
Contents |
Structure of human PNMT complexed with S-adenosyl-homocysteine and an inhibitor, trans-(1S,2S)-2-amino-1-tetralol
Template:ABSTRACT PUBMED 16363801
About this Structure
2an5 is a 2 chain structure of Phenylethanolamine N-methyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Gee CL, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL. Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis. Biochemistry. 2005 Dec 27;44(51):16875-85. PMID:16363801 doi:http://dx.doi.org/10.1021/bi051636b
