3hx7
From Proteopedia
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[[Image:3hx7.png|left|200px]] | [[Image:3hx7.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_19923220}} | {{ABSTRACT_PUBMED_19923220}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Basal ganglia disease, adult-onset OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134790 134790]], Hyperferritinemia-cataract syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=134790 134790]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3hx7]] is a 48 chain structure of [[Ferritin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HX7 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Ferritin]] | ||
==Reference== | ==Reference== | ||
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[[Category: Iron storage protein]] | [[Category: Iron storage protein]] | ||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 3 08:59:20 2010'' | ||
Revision as of 23:20, 26 December 2010
Crystal structure of human ferritin Phe167SerfsX26 mutant. This file is a part 3/3 of the split entry and contains the copies 5 and 6 of the total six copies of the biological unit that are present in the crystallographic asymmetric unit. The entire structure contains six copies of the biological unit in the crystallographic asymmetric unit and is described in remark 400
Template:ABSTRACT PUBMED 19923220
About this Structure
3hx7 is a 48 chain structure of Ferritin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Baraibar MA, Muhoberac BB, Garringer HJ, Hurley TD, Vidal R. Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration. J Biol Chem. 2010 Jan 15;285(3):1950-6. Epub 2009 Nov 18. PMID:19923220 doi:10.1074/jbc.M109.042986
- Baraibar MA, Barbeito AG, Muhoberac BB, Vidal R. Iron-mediated aggregation and a localized structural change characterize ferritin from a mutant light chain polypeptide that causes neurodegeneration. J Biol Chem. 2008 Nov 14;283(46):31679-89. Epub 2008 Aug 28. PMID:18755684 doi:10.1074/jbc.M805532200
