2p8h
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="2p8h" size="450" color="white" frame="true" align="right" spinBox="true" caption="2p8h, resolution 1.80Å" /> '''Crystal structure o...) |
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caption="2p8h, resolution 1.80Å" /> | caption="2p8h, resolution 1.80Å" /> | ||
'''Crystal structure of human beta secretase complexed with inhibitor'''<br /> | '''Crystal structure of human beta secretase complexed with inhibitor'''<br /> | ||
==About this Structure== | ==About this Structure== | ||
| - | 2P8H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with MY9 as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] Full crystallographic information is available from [http:// | + | 2P8H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MY9:'>MY9</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8H OCA]. |
==Reference== | ==Reference== | ||
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[[Category: hydrolase]] | [[Category: hydrolase]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 23 12:50:06 2008'' |
Revision as of 10:50, 23 January 2008
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Crystal structure of human beta secretase complexed with inhibitor
About this Structure
2P8H is a Single protein structure of sequence from Homo sapiens with as ligand. Active as Memapsin 2, with EC number 3.4.23.46 Full crystallographic information is available from OCA.
Reference
Design and Synthesis of 2,3,5-Substituted Imidazolidin-4-one Inhibitors of BACE-1., Barrow JC, Rittle KE, Ngo PL, Selnick HG, Graham SL, Pitzenberger SM, McGaughey GB, Colussi D, Lai MT, Huang Q, Tugusheva K, Espeseth AS, Simon AJ, Munshi SK, Vacca JP, ChemMedChem. 2007 Jul 9;2(7):995-999. PMID:17458843
Page seeded by OCA on Wed Jan 23 12:50:06 2008
Categories: Homo sapiens | Memapsin 2 | Single protein | Munshi, S. | MY9 | Aspartyl protease | Bace | Hydrolase
