Severin

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== 3D Structures of Severin ==
== 3D Structures of Severin ==
[[3fg6]] – Adseverin C-terminal – human<br />
[[3fg6]] – Adseverin C-terminal – human<br />
-
[[1svy]] – Severin domain 2 – ''Dictyostelium discoideum'' <br />
+
[[1svy]] – DdSeverin domain 2 – ''Dictyostelium discoideum'' <br />
-
[[1svq]] - Severin domain 2 - ''Dictyostelium discoideum'', NMR<br />
+
[[1svq]], [[1svr]] - DdSeverin domain 2 - ''Dictyostelium discoideum'', NMR<br />
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 07:27, 28 December 2010

Crystal Structure of Human Severin, 3fg6
Crystal Structure of Human Severin, 3fg6

Template:STRUCTURE 3fg6

Severin is a calcium-activated protein which binds actin. The images at the top and at the right correspond to one representative severin structure, i.e. the human severin (3fg6). It nucleates actin assembly, severes F-actin and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. It is named Adseverin and Scinderin as well. The image at the right is the severin with (colored lime).

3D Structures of Severin

3fg6 – Adseverin C-terminal – human
1svy – DdSeverin domain 2 – Dictyostelium discoideum
1svq, 1svr - DdSeverin domain 2 - Dictyostelium discoideum, NMR

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Jaime Prilusky

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