2hyy
From Proteopedia
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[[Image:2hyy.png|left|200px]] | [[Image:2hyy.png|left|200px]] | ||
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{{ABSTRACT_PUBMED_17164530}} | {{ABSTRACT_PUBMED_17164530}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Leukemia, Philadelphia chromosome-positive, resistant to imatinib OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=189980 189980]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2hyy]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HYY OCA]. | |
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| + | ==See Also== | ||
| + | *[[Imatinib]] | ||
==Reference== | ==Reference== | ||
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[[Category: Liebetanz, J.]] | [[Category: Liebetanz, J.]] | ||
[[Category: Manley, P.]] | [[Category: Manley, P.]] | ||
| + | [[Category: Transferase]] | ||
[[Category: Tyrosine kinase]] | [[Category: Tyrosine kinase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 00:39:09 2009'' | ||
Revision as of 13:14, 28 December 2010
Contents |
Human Abl kinase domain in complex with imatinib (STI571, Glivec)
Template:ABSTRACT PUBMED 17164530
About this Structure
2hyy is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Cowan-Jacob SW, Fendrich G, Floersheimer A, Furet P, Liebetanz J, Rummel G, Rheinberger P, Centeleghe M, Fabbro D, Manley PW. Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia. Acta Crystallogr D Biol Crystallogr. 2007 Jan;63(Pt 1):80-93. Epub 2006, Dec 13. PMID:17164530 doi:http://dx.doi.org/10.1107/S0907444906047287
