3pjc

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'''Unreleased structure'''
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[[Image:3pjc.jpg|left|200px]]
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The entry 3pjc is ON HOLD until Paper Publication
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{{STRUCTURE_3pjc| PDB=3pjc | SCENE= }}
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Authors: Tavares, G.A., Thoma, G., Zerwes, H.-G., Kroemer, M.
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===Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family===
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Description: Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 8 11:32:03 2010''
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{{ABSTRACT_PUBMED_21155605}}
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==About this Structure==
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[[3pjc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJC OCA].
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==Reference==
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<ref group="xtra">PMID:21155605</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Kroemer, M.]]
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[[Category: Tavares, G A.]]
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[[Category: Thoma, G.]]
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[[Category: Zerwes, H G.]]
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[[Category: Atp site kinase inhibitor]]
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[[Category: Atp-binding]]
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[[Category: Small molecule inhibitor]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 18:40, 29 December 2010

Image:3pjc.jpg

Template:STRUCTURE 3pjc

Crystal structure of JAK3 complexed with a potent ATP site inhibitor showing high selectivity within the Janus kinase family

Template:ABSTRACT PUBMED 21155605

About this Structure

3pjc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Thoma G, Nuninger F, Falchetto R, Hermes E, Tavares GA, Vangrevelinghe E, Zerwes HG. Identification of a Potent Janus Kinase 3 Inhibitor with High Selectivity within the Janus Kinase Family. J Med Chem. 2010 Dec 14. PMID:21155605 doi:10.1021/jm101157q

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