Leukotriene A4 Hydrolase
From Proteopedia
| Line 2: | Line 2: | ||
{{STRUCTURE_2xpz| PDB=2xpz | SIZE=300| SCENE=Subtilisin/Cv/1 |right|CAPTION=Leukotriene A4 Hydrolase [[2xpz]] }} | {{STRUCTURE_2xpz| PDB=2xpz | SIZE=300| SCENE=Subtilisin/Cv/1 |right|CAPTION=Leukotriene A4 Hydrolase [[2xpz]] }} | ||
| - | Leukotriene A4 Hydrolase (LTA4H) is an aminopeptidase which converts leukotriene A4 to leukotriene B4 as part of the arachidonic acid metabolism. The images at the left and at the right correspond to one representative LTA4H, ''i.e.'' the crystal structure of yeast Leukotriene A4 Hydrolase ([[2xpz]]). | + | [[Leukotriene A4 Hydrolase]] (LTA4H) is an aminopeptidase which converts leukotriene A4 to leukotriene B4 as part of the arachidonic acid metabolism. The images at the left and at the right correspond to one representative LTA4H, ''i.e.'' the crystal structure of yeast Leukotriene A4 Hydrolase ([[2xpz]]). |
{{TOC limit|limit=2}} | {{TOC limit|limit=2}} | ||
Revision as of 12:36, 30 December 2010
Leukotriene A4 Hydrolase (LTA4H) is an aminopeptidase which converts leukotriene A4 to leukotriene B4 as part of the arachidonic acid metabolism. The images at the left and at the right correspond to one representative LTA4H, i.e. the crystal structure of yeast Leukotriene A4 Hydrolase (2xpz).
3D Structures of Leukotriene A4 Hydrolase
1xpy, 2xpz – yLTA4H – yeast
2xq0 – yLTA4H+bestatin
3fh5, 3fh7, 3fh8, 3fhe, 3ful, 3fum, 3fun – hLTA4H+pyrrolidine derivative – human
1sqm, 1gw6, 1h19 - hLTA4H (mutant)
1hs6 - hLTA4H+bestatin
3ftz, 3ftv, 3ftw, 3ftx, 3fui - hLTA4H+aniline derivative
3fts, 3ftu - hLTA4H+resveratrol derivative
3fty, 3fu0 - hLTA4H+pyridine derivative
3fu3, 3fu5, 3fu6, 3fud - hLTA4H+thio derivative
3fue, 3fuf, 3fuh - hLTA4H+bestatin+indole derivative
3fuj, 3fuk - hLTA4H+indole derivative
3b7r, 3r59, 3cho, 3chp, 3chq, 3chr, 3chs - hLTA4H+inhibitor
3b7u - hLTA4H+kelatorphan
2vj8 - hLTA4H+hydroxamic acid
3b7s, 3b7t - hLTA4H (mutant)+tripeptide
