2p8s

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==About this Structure==
==About this Structure==
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2P8S is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8S OCA].
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[[2p8s]] is a 2 chain structure of [[Dipeptidyl peptidase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P8S OCA].
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==See Also==
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*[[Dipeptidyl peptidase]]
==Reference==
==Reference==
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[[Category: Beta-propeller]]
[[Category: Beta-propeller]]
[[Category: Dimer]]
[[Category: Dimer]]
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[[Category: Hydrolase]]
[[Category: Structure-based design]]
[[Category: Structure-based design]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:53:49 2009''
 

Revision as of 11:50, 3 January 2011

Template:STRUCTURE 2p8s

Contents

Human dipeptidyl peptidase IV/CD26 in complex with a cyclohexalamine inhibitor

Template:ABSTRACT PUBMED 17433672

About this Structure

2p8s is a 2 chain structure of Dipeptidyl peptidase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Biftu T, Scapin G, Singh S, Feng D, Becker JW, Eiermann G, He H, Lyons K, Patel S, Petrov A, Sinha-Roy R, Zhang B, Wu J, Zhang X, Doss GA, Thornberry NA, Weber AE. Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3384-7. Epub 2007 Apr 2. PMID:17433672 doi:10.1016/j.bmcl.2007.03.095

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