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3phe

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Revision as of 15:38, 5 January 2011

Image:3phe.png

Template:STRUCTURE 3phe

HCV NS5B with a bound quinolone inhibitor

Template:ABSTRACT PUBMED 21145235

About this Structure

3phe is a 4 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

Kumar DV, Rai R, Brameld KA, Somoza JR, Rajagopalan R, Janc JW, Xia YM, Ton TL, Shaghafi MB, Hu H, Lehoux I, To N, Young WB, Green MJ. Quinolones as HCV NS5B polymerase inhibitors. Bioorg Med Chem Lett. 2011 Jan 1;21(1):82-7. Epub 2010 Nov 21. PMID:21145235 doi:10.1016/j.bmcl.2010.11.068