1o4x

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{{Seed}}
 
[[Image:1o4x.png|left|200px]]
[[Image:1o4x.png|left|200px]]
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{{ABSTRACT_PUBMED_14559893}}
{{ABSTRACT_PUBMED_14559893}}
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==Disease==
 
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Known disease associated with this structure: Microphthalmia, syndromic 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=184429 184429]], Optic nerve hypoplasia and abnormalities of the central nervous system OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=184429 184429]]
 
==About this Structure==
==About this Structure==
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1O4X is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The April 2009 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Oct and Sox Transcription Factors'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2009_4 10.2210/rcsb_pdb/mom_2009_4]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4X OCA].
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[[1o4x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The April 2009 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Oct and Sox Transcription Factors'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2009_4 10.2210/rcsb_pdb/mom_2009_4]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4X OCA].
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==See Also==
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*[[Teaching Scenes%2C Tutorials%2C and Educators' Pages]]
==Reference==
==Reference==
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[[Category: Transcription factor]]
[[Category: Transcription factor]]
[[Category: Transcription/dna complex]]
[[Category: Transcription/dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 08:58:06 2010''
 

Revision as of 04:12, 6 January 2011

Template:STRUCTURE 1o4x

Contents

TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT

Template:ABSTRACT PUBMED 14559893

About this Structure

1o4x is a 4 chain structure with sequence from Homo sapiens. The April 2009 RCSB PDB Molecule of the Month feature on Oct and Sox Transcription Factors by David Goodsell is 10.2210/rcsb_pdb/mom_2009_4. Full experimental information is available from OCA.

See Also

Reference

  • Williams DC Jr, Cai M, Clore GM. Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex. J Biol Chem. 2004 Jan 9;279(2):1449-57. Epub 2003 Oct 14. PMID:14559893 doi:http://dx.doi.org/10.1074/jbc.M309790200

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