Chymotrypsin Inhibitor
From Proteopedia
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{{STRUCTURE_4wbc| PDB=4wbc | SIZE=300| SCENE=Chymotrypsin_Inhibitor/Cv/1 |right|CAPTION=Chymotrypsin Inhibitor [[4wbc]] }} | {{STRUCTURE_4wbc| PDB=4wbc | SIZE=300| SCENE=Chymotrypsin_Inhibitor/Cv/1 |right|CAPTION=Chymotrypsin Inhibitor [[4wbc]] }} | ||
| - | [[Chymotrypsin Inhibitor|Chymotrypsin Inhibitors]] are serine proteinase inhibitors of chymotrypsin. They are classified by numbers: CI-1, CI-2, CI-3. The images at the left and at the right correspond to one representative Chymotrypsin Inhibitor, ''i.e.'' the crystal structure of Chymotrypsin Inhibitor from ''Phosphocarpus tetragonolobus'' ([[4wbc]]). | + | [[Chymotrypsin Inhibitor|Chymotrypsin Inhibitors]] (CI) are serine proteinase inhibitors of chymotrypsin. They are classified by numbers: CI-1, CI-2, CI-3. The images at the left and at the right correspond to one representative Chymotrypsin Inhibitor, ''i.e.'' the crystal structure of Chymotrypsin Inhibitor from ''Phosphocarpus tetragonolobus'' ([[4wbc]]). |
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== 3D Structures of Chymotrypsin Inhibitor == | == 3D Structures of Chymotrypsin Inhibitor == | ||
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[[2jzm]] – CI-1 fragment – ''Nicotiana alata'' – NMR<br /> | [[2jzm]] – CI-1 fragment – ''Nicotiana alata'' – NMR<br /> | ||
| - | [[1eai]] – CI-1+elastase - pig | + | [[1eai]] – CI-1+elastase - pig<br /> |
| + | [[1kgm]] –lCI-1 – locust<br /> | ||
| + | [[1kio]] – lCI-1 (mutant)<br /> | ||
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[[1cis]] - HvCI-2+subtilisin helix – NMR<br /> | [[1cis]] - HvCI-2+subtilisin helix – NMR<br /> | ||
[[3ci2]] - HvCI-2 – NMR<br /> | [[3ci2]] - HvCI-2 – NMR<br /> | ||
| - | [[2ci2]] - HvCI-2 | + | [[2ci2]] - HvCI-2<br /> |
| - | + | [[1cq4]] - HvCI-2 domain swap | |
=== CI-3 === | === CI-3 === | ||
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[[3i2a]], [[3i2x]], [[2bea]], [[2beb]], [[2esu]], [[2et2]], [[1xg6]], [[1fmz]], [[1fn0]], [[1eyl]] – PtCI-3 (mutant) – ''Phosphocarpus tetragonolobus''<br /> | [[3i2a]], [[3i2x]], [[2bea]], [[2beb]], [[2esu]], [[2et2]], [[1xg6]], [[1fmz]], [[1fn0]], [[1eyl]] – PtCI-3 (mutant) – ''Phosphocarpus tetragonolobus''<br /> | ||
[[4wbc]], [[2wbc]], [[1wbc]] - PtCI-3<br /> | [[4wbc]], [[2wbc]], [[1wbc]] - PtCI-3<br /> | ||
| + | [[3i29]] - PtCI-3 (mutant)+trypsin<br /> | ||
[[2qyi]] – CI-3 (mutant)+cationic trypsin – cow<br /> | [[2qyi]] – CI-3 (mutant)+cationic trypsin – cow<br /> | ||
| - | [[1ccv]] – CI –''Apis mellifera'' - NMR | + | [[1ccv]] – CI –''Apis mellifera'' - NMR<br /> |
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:40, 27 January 2011
Chymotrypsin Inhibitors (CI) are serine proteinase inhibitors of chymotrypsin. They are classified by numbers: CI-1, CI-2, CI-3. The images at the left and at the right correspond to one representative Chymotrypsin Inhibitor, i.e. the crystal structure of Chymotrypsin Inhibitor from Phosphocarpus tetragonolobus (4wbc).
3D Structures of Chymotrypsin Inhibitor
CI-1
2jzm – CI-1 fragment – Nicotiana alata – NMR
1eai – CI-1+elastase - pig
1kgm –lCI-1 – locust
1kio – lCI-1 (mutant)
CI-2
1y1k, 1y33, 1y34, 1y3b, 1y3c, 1y3d, 1y3f, 1y48, 1y4a, 1y4d, 1tm1, 1tm3, 1tm4, 1tm5, 1tm7, 1tmg, 1to1, 1to2, 1lw6 – BaCI-2 (mutant)+subtilisin – Bacillus amyloliquefaciens
2sni - BaCI-2+subtilisin
1ciq, 1cir – HvCI-2 fragments – Hordeum vulgare
1coa, 1ypa, 1ypb, 1ypc – HvCI-2 (mutant)
1cis - HvCI-2+subtilisin helix – NMR
3ci2 - HvCI-2 – NMR
2ci2 - HvCI-2
1cq4 - HvCI-2 domain swap
CI-3
3i2a, 3i2x, 2bea, 2beb, 2esu, 2et2, 1xg6, 1fmz, 1fn0, 1eyl – PtCI-3 (mutant) – Phosphocarpus tetragonolobus
4wbc, 2wbc, 1wbc - PtCI-3
3i29 - PtCI-3 (mutant)+trypsin
2qyi – CI-3 (mutant)+cationic trypsin – cow
1ccv – CI –Apis mellifera - NMR
