3lox

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'''Unreleased structure'''
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[[Image:3lox.jpg|left|200px]]
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The entry 3lox is ON HOLD until sometime in the future
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{{STRUCTURE_3lox| PDB=3lox | SCENE= }}
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Authors: Prongay, A.J.
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===HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound===
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Description: HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound.
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 5 11:36:49 2010''
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{{ABSTRACT_PUBMED_20303756}}
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==About this Structure==
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[[3lox]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LOX OCA].
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==Reference==
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<ref group="xtra">PMID:20303756</ref><references group="xtra"/>
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[[Category: Hepatitis c virus subtype 1a]]
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[[Category: Prongay, A J.]]

Revision as of 09:57, 23 February 2011

Image:3lox.jpg

Template:STRUCTURE 3lox

HCV NS3-4a protease domain with a ketoamide inhibitor derivative of Boceprevir bound

Template:ABSTRACT PUBMED 20303756

About this Structure

3lox is a 4 chain structure with sequence from Hepatitis c virus subtype 1a. Full crystallographic information is available from OCA.

Reference

  • Bennett F, Huang Y, Hendrata S, Lovey R, Bogen SL, Pan W, Guo Z, Prongay A, Chen KX, Arasappan A, Venkatraman S, Velazquez F, Nair L, Sannigrahi M, Tong X, Pichardo J, Cheng KC, Girijavallabhan VM, Saksena AK, Njoroge FG. The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir: a change in direction in the search for a second generation HCV NS3 protease inhibitor. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2617-21. Epub 2010 Feb 19. PMID:20303756 doi:10.1016/j.bmcl.2010.02.063

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