3img

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{{Seed}}
 
[[Image:3img.png|left|200px]]
[[Image:3img.png|left|200px]]
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==About this Structure==
==About this Structure==
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3IMG is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMG OCA].
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[[3img]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IMG OCA].
==Reference==
==Reference==
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[[Category: Silvestre, H L.]]
[[Category: Silvestre, H L.]]
[[Category: Wen, S.]]
[[Category: Wen, S.]]
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[[Category: Atp-binding]]
 
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[[Category: Cytoplasm]]
 
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[[Category: Drug design]]
 
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[[Category: Enzyme]]
 
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[[Category: Fragment-based]]
 
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[[Category: Ligase]]
 
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[[Category: Magnesium]]
 
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[[Category: Metal-binding]]
 
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[[Category: Mycobacterium tuberculosis]]
 
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[[Category: Nucleotide-binding]]
 
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[[Category: Pantothenate biosynthesis]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 11 20:28:40 2009''
 

Revision as of 06:22, 2 March 2011

Template:STRUCTURE 3img

Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.8 Ang resolution in a ternary complex with fragment compounds 5-methoxyindole and 1-benzofuran-2-carboxylic acid

About this Structure

3img is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Hung AW, Silvestre HL, Wen S, Ciulli A, Blundell TL, Abell C. Application of fragment growing and fragment linking to the discovery of inhibitors of Mycobacterium tuberculosis pantothenate synthetase. Angew Chem Int Ed Engl. 2009;48(45):8452-6. PMID:19780086 doi:10.1002/anie.200903821

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