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2uxx
From Proteopedia
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| - | {{Seed}} | ||
[[Image:2uxx.png|left|200px]] | [[Image:2uxx.png|left|200px]] | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[2uxx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXX OCA]. | |
==Reference== | ==Reference== | ||
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[[Category: Nucleosome]] | [[Category: Nucleosome]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
| + | [[Category: Oxidoreductase/repressor]] | ||
[[Category: Oxidoreductase/repressor complex]] | [[Category: Oxidoreductase/repressor complex]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
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[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
[[Category: Tranylcypromine]] | [[Category: Tranylcypromine]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 10:22:11 2009'' | ||
Revision as of 18:28, 14 March 2011
HUMAN LSD1 HISTONE DEMETHYLASE-COREST IN COMPLEX WITH AN FAD-TRANYLCYPROMINE ADDUCT
Template:ABSTRACT PUBMED 17569509
About this Structure
2uxx is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Yang M, Culhane JC, Szewczuk LM, Jalili P, Ball HL, Machius M, Cole PA, Yu H. Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine. Biochemistry. 2007 Jul 10;46(27):8058-65. Epub 2007 Jun 15. PMID:17569509 doi:10.1021/bi700664y
- Yang M, Gocke CB, Luo X, Borek D, Tomchick DR, Machius M, Otwinowski Z, Yu H. Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase. Mol Cell. 2006 Aug 4;23(3):377-87. PMID:16885027 doi:http://dx.doi.org/10.1016/j.molcel.2006.07.012
Categories: Homo sapiens | Cole, P A. | Culhane, J C. | Machius, M. | Yang, M. | Yu, H. | Alternative splicing | Chromatin demethylation | Chromatin regulator | Coiled coil | Corest | Depression | Fad | Histone demethylase | Host-virus interaction | Lsd1 | Nuclear protein | Nucleosome | Oxidoreductase | Oxidoreductase/repressor | Oxidoreductase/repressor complex | Phosphorylation | Repressor | Transcription | Transcription regulation | Tranylcypromine
