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1h7x

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{{Seed}}
 
[[Image:1h7x.png|left|200px]]
[[Image:1h7x.png|left|200px]]
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==About this Structure==
==About this Structure==
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1H7X is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7X OCA].
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[[1h7x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7X OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:11179210</ref><references group="xtra"/>
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<ref group="xtra">PMID:11179210</ref><ref group="xtra">PMID:11134942</ref><references group="xtra"/>
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
[[Category: Dobritzsch, D.]]
[[Category: Dobritzsch, D.]]
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[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Pyrimidine catabolism]]
[[Category: Pyrimidine catabolism]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 07:48:23 2009''
 

Revision as of 19:08, 14 March 2011

Image:1h7x.png

Template:STRUCTURE 1h7x

DIHYDROPYRIMIDINE DEHYDROGENASE (DPD) FROM PIG, TERNARY COMPLEX OF A MUTANT ENZYME (C671A), NADPH AND 5-FLUOROURACIL

Template:ABSTRACT PUBMED 11179210

About this Structure

1h7x is a 4 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA.

Reference

  • Dobritzsch D, Schneider G, Schnackerz KD, Lindqvist Y. Crystal structure of dihydropyrimidine dehydrogenase, a major determinant of the pharmacokinetics of the anti-cancer drug 5-fluorouracil. EMBO J. 2001 Feb 15;20(4):650-60. PMID:11179210 doi:10.1093/emboj/20.4.650
  • Dobritzsch D, Persson K, Schneider G, Lindqvist Y. Crystallization and preliminary X-ray study of pig liver dihydropyrimidine dehydrogenase. Acta Crystallogr D Biol Crystallogr. 2001 Jan;57(Pt 1):153-5. PMID:11134942

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