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1e74

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[[Image:1e74.png|left|200px]]
[[Image:1e74.png|left|200px]]
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==About this Structure==
==About this Structure==
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1E74 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Conus_imperialis Conus imperialis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E74 OCA].
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[[1e74]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E74 OCA].
==Reference==
==Reference==
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Structure-activity relationships in a peptidic alpha7 nicotinic acetylcholine receptor antagonist., Rogers JP, Luginbuhl P, Pemberton K, Harty P, Wemmer DE, Stevens RC, J Mol Biol. 2000 Dec 15;304(5):911-26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11124036 11124036]
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<ref group="xtra">PMID:11124036</ref><ref group="xtra">PMID:10194298</ref><ref group="xtra">PMID:7651351</ref><ref group="xtra">PMID:8206995</ref><references group="xtra"/>
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[[Category: Conus imperialis]]
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[[Category: Single protein]]
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[[Category: Harty, P.]]
[[Category: Harty, P.]]
[[Category: Luginbuhl, P.]]
[[Category: Luginbuhl, P.]]
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[[Category: Nmr solution structure]]
[[Category: Nmr solution structure]]
[[Category: Peptide toxin]]
[[Category: Peptide toxin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:15:46 2008''
 

Revision as of 20:05, 14 March 2011

Image:1e74.png

Template:STRUCTURE 1e74

NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT R11E

Template:ABSTRACT PUBMED 11124036

About this Structure

1e74 is a 1 chain structure. Full experimental information is available from OCA.

Reference

  • Rogers JP, Luginbuhl P, Pemberton K, Harty P, Wemmer DE, Stevens RC. Structure-activity relationships in a peptidic alpha7 nicotinic acetylcholine receptor antagonist. J Mol Biol. 2000 Dec 15;304(5):911-26. PMID:11124036 doi:10.1006/jmbi.2000.4247
  • Rogers JP, Luginbuhl P, Shen GS, McCabe RT, Stevens RC, Wemmer DE. NMR solution structure of alpha-conotoxin ImI and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors. Biochemistry. 1999 Mar 30;38(13):3874-82. PMID:10194298 doi:10.1021/bi9826254
  • Johnson DS, Martinez J, Elgoyhen AB, Heinemann SF, McIntosh JM. alpha-Conotoxin ImI exhibits subtype-specific nicotinic acetylcholine receptor blockade: preferential inhibition of homomeric alpha 7 and alpha 9 receptors. Mol Pharmacol. 1995 Aug;48(2):194-9. PMID:7651351
  • McIntosh JM, Yoshikami D, Mahe E, Nielsen DB, Rivier JE, Gray WR, Olivera BM. A nicotinic acetylcholine receptor ligand of unique specificity, alpha-conotoxin ImI. J Biol Chem. 1994 Jun 17;269(24):16733-9. PMID:8206995

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