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1v7m

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Revision as of 20:50, 14 March 2011

Image:1v7m.png

Template:STRUCTURE 1v7m

Human Thrombopoietin Functional Domain Complexed To Neutralizing Antibody TN1 Fab

Template:ABSTRACT PUBMED 14769915

About this Structure

1v7m is a 6 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Feese MD, Tamada T, Kato Y, Maeda Y, Hirose M, Matsukura Y, Shigematsu H, Muto T, Matsumoto A, Watarai H, Ogami K, Tahara T, Kato T, Miyazaki H, Kuroki R. Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment. Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):1816-21. Epub 2004 Feb 9. PMID:14769915 doi:http://dx.doi.org/10.1073/pnas.0308530100
  • Kuroki R, Hirose M, Kato Y, Feese MD, Tamada T, Shigematsu H, Watarai H, Maeda Y, Tahara T, Kato T, Miyazaki H. Crystallization of the functional domain of human thrombopoietin using an antigen-binding fragment derived from neutralizing monoclonal antibody. Acta Crystallogr D Biol Crystallogr. 2002 May;58(Pt 5):856-8. Epub 2002, Apr 26. PMID:11976502

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OCA

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