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2fie

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[[Image:2fie.png|left|200px]]
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==About this Structure==
==About this Structure==
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2FIE is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIE OCA].
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[[2fie]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIE OCA].
==Reference==
==Reference==
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[[Category: Allosteric inhibitors human liver fbpase]]
[[Category: Allosteric inhibitors human liver fbpase]]
[[Category: Benzoxazole]]
[[Category: Benzoxazole]]
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[[Category: Hydrolase]]
[[Category: Intersubunit allosteric inhibitors of human liver fbpase]]
[[Category: Intersubunit allosteric inhibitors of human liver fbpase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:38:54 2009''
 

Revision as of 23:29, 14 March 2011

Template:STRUCTURE 2fie

Structure of human liver FBPase complexed with potent benzoxazole allosteric inhibitors

Template:ABSTRACT PUBMED 16446092

About this Structure

2fie is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Lai C, Gum RJ, Daly M, Fry EH, Hutchins C, Abad-Zapatero C, von Geldern TW. Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1807-10. Epub 2006 Jan 30. PMID:16446092 doi:10.1016/j.bmcl.2006.01.014
  • von Geldern TW, Lai C, Gum RJ, Daly M, Sun C, Fry EH, Abad-Zapatero C. Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode. Bioorg Med Chem Lett. 2006 Apr 1;16(7):1811-5. Epub 2006 Jan 25. PMID:16442285 doi:10.1016/j.bmcl.2006.01.015

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