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1e1y
From Proteopedia
(Difference between revisions)
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| - | {{Seed}} | ||
[[Image:1e1y.png|left|200px]] | [[Image:1e1y.png|left|200px]] | ||
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{{STRUCTURE_1e1y| PDB=1e1y | SCENE= }} | {{STRUCTURE_1e1y| PDB=1e1y | SCENE= }} | ||
| - | === | + | ===FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE=== |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1e1y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E1Y OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:10924512</ref><references group="xtra"/> | + | <ref group="xtra">PMID:10924512</ref><ref group="xtra">PMID:10548038</ref><ref group="xtra">PMID:9384557</ref><references group="xtra"/> |
[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
[[Category: Phosphorylase]] | [[Category: Phosphorylase]] | ||
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[[Category: Inhibitor site]] | [[Category: Inhibitor site]] | ||
[[Category: X-ray crystallography]] | [[Category: X-ray crystallography]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 15:09:48 2009'' | ||
Revision as of 23:30, 14 March 2011
FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE
Template:ABSTRACT PUBMED 10924512
About this Structure
1e1y is a 1 chain structure with sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.
Reference
- Oikonomakos NG, Schnier JB, Zographos SE, Skamnaki VT, Tsitsanou KE, Johnson LN. Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site. J Biol Chem. 2000 Nov 3;275(44):34566-73. PMID:10924512 doi:http://dx.doi.org/10.1074/jbc.M004485200
- Oikonomakos NG, Tsitsanou KE, Zographos SE, Skamnaki VT, Goldmann S, Bischoff H. Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate. Protein Sci. 1999 Oct;8(10):1930-45. PMID:10548038
- Zographos SE, Oikonomakos NG, Tsitsanou KE, Leonidas DD, Chrysina ED, Skamnaki VT, Bischoff H, Goldmann S, Watson KA, Johnson LN. The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor. Structure. 1997 Nov 15;5(11):1413-25. PMID:9384557
