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2cbq

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Revision as of 23:58, 14 March 2011

Image:2cbq.png

Template:STRUCTURE 2cbq

CRYSTAL STRUCTURE OF THE NEOCARZINOSTATIN 1TES15 MUTANT BOUND TO TESTOSTERONE HEMISUCCINATE.

Template:ABSTRACT PUBMED 16529771

About this Structure

2cbq is a 6 chain structure with sequence from Streptomyces carzinostaticus. Full crystallographic information is available from OCA.

Reference

  • Drevelle A, Graille M, Heyd B, Sorel I, Ulryck N, Pecorari F, Desmadril M, van Tilbeurgh H, Minard P. Structures of in vitro evolved binding sites on neocarzinostatin scaffold reveal unanticipated evolutionary pathways. J Mol Biol. 2006 Apr 28;358(2):455-71. Epub 2006 Feb 20. PMID:16529771 doi:10.1016/j.jmb.2006.02.002
  • Heyd B, Pecorari F, Collinet B, Adjadj E, Desmadril M, Minard P. In vitro evolution of the binding specificity of neocarzinostatin, an enediyne-binding chromoprotein. Biochemistry. 2003 May 20;42(19):5674-83. PMID:12741824 doi:10.1021/bi0273664

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OCA

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