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1e76

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Revision as of 00:33, 15 March 2011

Image:1e76.png

Template:STRUCTURE 1e76

NMR SOLUTION STRUCTURE OF ALPHA-CONOTOXIN IM1 POINT MUTATION VARIANT D5N

Template:ABSTRACT PUBMED 11124036

About this Structure

1e76 is a 1 chain structure. Full experimental information is available from OCA.

Reference

  • Rogers JP, Luginbuhl P, Pemberton K, Harty P, Wemmer DE, Stevens RC. Structure-activity relationships in a peptidic alpha7 nicotinic acetylcholine receptor antagonist. J Mol Biol. 2000 Dec 15;304(5):911-26. PMID:11124036 doi:10.1006/jmbi.2000.4247
  • Rogers JP, Luginbuhl P, Shen GS, McCabe RT, Stevens RC, Wemmer DE. NMR solution structure of alpha-conotoxin ImI and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors. Biochemistry. 1999 Mar 30;38(13):3874-82. PMID:10194298 doi:10.1021/bi9826254
  • Johnson DS, Martinez J, Elgoyhen AB, Heinemann SF, McIntosh JM. alpha-Conotoxin ImI exhibits subtype-specific nicotinic acetylcholine receptor blockade: preferential inhibition of homomeric alpha 7 and alpha 9 receptors. Mol Pharmacol. 1995 Aug;48(2):194-9. PMID:7651351
  • McIntosh JM, Yoshikami D, Mahe E, Nielsen DB, Rivier JE, Gray WR, Olivera BM. A nicotinic acetylcholine receptor ligand of unique specificity, alpha-conotoxin ImI. J Biol Chem. 1994 Jun 17;269(24):16733-9. PMID:8206995

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