This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1wut

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
{{Seed}}
 
[[Image:1wut.png|left|200px]]
[[Image:1wut.png|left|200px]]
Line 20: Line 19:
==About this Structure==
==About this Structure==
-
1WUT is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUT OCA].
+
[[1wut]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUT OCA].
==Reference==
==Reference==
Line 40: Line 39:
[[Category: Wendt, K U.]]
[[Category: Wendt, K U.]]
[[Category: Glycogenolysis]]
[[Category: Glycogenolysis]]
 +
[[Category: Transferase]]
[[Category: Type 2 diabetes]]
[[Category: Type 2 diabetes]]
- 
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:40:12 2009''
 

Revision as of 00:41, 15 March 2011

Image:1wut.png

Template:STRUCTURE 1wut

Acyl Ureas as Human Liver Glycogen Phosphorylase Inhibitors for the Treatment of Type 2 Diabetes

Template:ABSTRACT PUBMED 15987904

About this Structure

1wut is a 1 chain structure with sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.

Reference

  • Oikonomakos NG, Kosmopoulou MN, Chrysina ED, Leonidas DD, Kostas ID, Wendt KU, Klabunde T, Defossa E. Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs. Protein Sci. 2005 Jul;14(7):1760-71. PMID:15987904 doi:14/7/1760
  • Oikonomakos NG, Skamnaki VT, Tsitsanou KE, Gavalas NG, Johnson LN. A new allosteric site in glycogen phosphorylase b as a target for drug interactions. Structure. 2000 Jun 15;8(6):575-84. PMID:10873856
  • Zographos SE, Oikonomakos NG, Tsitsanou KE, Leonidas DD, Chrysina ED, Skamnaki VT, Bischoff H, Goldmann S, Watson KA, Johnson LN. The structure of glycogen phosphorylase b with an alkyldihydropyridine-dicarboxylic acid compound, a novel and potent inhibitor. Structure. 1997 Nov 15;5(11):1413-25. PMID:9384557
  • Rath VL, Ammirati M, Danley DE, Ekstrom JL, Gibbs EM, Hynes TR, Mathiowetz AM, McPherson RK, Olson TV, Treadway JL, Hoover DJ. Human liver glycogen phosphorylase inhibitors bind at a new allosteric site. Chem Biol. 2000 Sep;7(9):677-82. PMID:10980448
  • Lu Z, Bohn J, Bergeron R, Deng Q, Ellsworth KP, Geissler WM, Harris G, McCann PE, McKeever B, Myers RW, Saperstein R, Willoughby CA, Yao J, Chapman K. A new class of glycogen phosphorylase inhibitors. Bioorg Med Chem Lett. 2003 Nov 17;13(22):4125-8. PMID:14592521

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1wut"
Personal tools