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3nz7

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[[Image:3nz7.png|left|200px]]
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===A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine ligand containing bis-3-fluoropyrrolidine end side chains===
===A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine ligand containing bis-3-fluoropyrrolidine end side chains===
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The line below this paragraph, {{ABSTRACT_PUBMED_21221451}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 21221451 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21221451}}
==About this Structure==
==About this Structure==
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3NZ7 is a 2 chains structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NZ7 OCA].
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[[3nz7]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NZ7 OCA].
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==Reference==
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<ref group="xtra">PMID:21221451</ref><references group="xtra"/>
[[Category: Campbell, N H.]]
[[Category: Campbell, N H.]]
[[Category: Neidle, S.]]
[[Category: Neidle, S.]]
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[[Category: Acridine]]
 
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[[Category: Anti-parallel]]
 
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[[Category: Bimolecular]]
 
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[[Category: Bsu-6039]]
 
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[[Category: Bsu6039]]
 
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[[Category: Dna]]
 
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[[Category: Fluorination]]
 
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[[Category: G-quadruplex]]
 
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[[Category: Macromolecule]]
 
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[[Category: Oxtyricha nova]]
 
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[[Category: Quadruplex]]
 
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[[Category: Telomere]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 09:02:55 2010''
 

Revision as of 07:29, 30 March 2011

Template:STRUCTURE 3nz7

A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine ligand containing bis-3-fluoropyrrolidine end side chains

Template:ABSTRACT PUBMED 21221451

About this Structure

3nz7 is a 2 chain structure. Full crystallographic information is available from OCA.

Reference

  • Campbell NH, Smith DL, Reszka AP, Neidle S, O'Hagan D. Fluorine in medicinal chemistry: beta-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNA. Org Biomol Chem. 2011 Mar 7;9(5):1328-31. Epub 2011 Jan 10. PMID:21221451 doi:10.1039/c0ob00886a

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