1aj1
From Proteopedia
(New page: 200px<br /> <applet load="1aj1" size="450" color="white" frame="true" align="right" spinBox="true" caption="1aj1" /> '''NMR STRUCTURE OF THE LANTIBIOTIC ACTAGARDIN...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1AJ1 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/ ]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1AJ1 OCA]]. | + | 1AJ1 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Actinoplanes_liguriae_and_actinoplanes_garbadinensis Actinoplanes liguriae and actinoplanes garbadinensis]]. Structure known Active Site: MER. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1AJ1 OCA]]. |
==Reference== | ==Reference== | ||
The three-dimensional solution structure of the lantibiotic murein-biosynthesis-inhibitor actagardine determined by NMR., Zimmermann N, Jung G, Eur J Biochem. 1997 Jun 15;246(3):809-19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9219543 9219543] | The three-dimensional solution structure of the lantibiotic murein-biosynthesis-inhibitor actagardine determined by NMR., Zimmermann N, Jung G, Eur J Biochem. 1997 Jun 15;246(3):809-19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9219543 9219543] | ||
| + | [[Category: Actinoplanes liguriae and actinoplanes garbadinensis]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Jung, G.]] | [[Category: Jung, G.]] | ||
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[[Category: transglycosylase inhibitor]] | [[Category: transglycosylase inhibitor]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 11:51:28 2007'' |
Revision as of 09:46, 30 October 2007
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NMR STRUCTURE OF THE LANTIBIOTIC ACTAGARDINE, 15 STRUCTURES
Overview
The three-dimensional solution structure of the lantibiotic actagardine, was determined at high resolution by homonuclear and heteronuclear, two-dimensional and three-dimensional NMR spectroscopy in, [2H3]acetonitrile/H2O (7:3). 133 non-trivial distance and 22, torsional-angle constraints were derived from the NMR data. An ensemble of, 15 low-energy structures was calculated by distance geometry followed by, an iterative relaxation-matrix-refinement procedure. The rmsd of the, backbone coordinates with respect to the average structure was 17 pm. The, two distinct thioether ring systems 1-6 and 7-19 were even better defined, with backbone rmsd of 10 pm and 14 pm, respectively. Actagardine shows a, rigid compact globular shape based on the constraining bridging pattern, which is composed of ... [(full description)]
About this Structure
1AJ1 is a [Single protein] structure of sequence from [Actinoplanes liguriae and actinoplanes garbadinensis]. Structure known Active Site: MER. Full crystallographic information is available from [OCA].
Reference
The three-dimensional solution structure of the lantibiotic murein-biosynthesis-inhibitor actagardine determined by NMR., Zimmermann N, Jung G, Eur J Biochem. 1997 Jun 15;246(3):809-19. PMID:9219543
Page seeded by OCA on Tue Oct 30 11:51:28 2007
