Aldehyde dehydrogenase

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(New page: Crystal Structure of Aldehyde dehydrogenase, 1nzx {{STRUCTURE_1nzx| PDB=1nzx | SIZE=300| SCENE= |right|CAPTION=Human aldehyde hydrogenase class 2 ...)
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[[Image:1nzx.png|left|200px|thumb|Crystal Structure of Aldehyde dehydrogenase, [[1nzx]]]]
[[Image:1nzx.png|left|200px|thumb|Crystal Structure of Aldehyde dehydrogenase, [[1nzx]]]]
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{{STRUCTURE_1nzx| PDB=1nzx | SIZE=300| SCENE= |right|CAPTION=Human aldehyde hydrogenase class 2 complex with NAD , [[1nzx]] }}
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{{STRUCTURE_1nzx| PDB=1nzx | SIZE=300| SCENE=Aldehyde_dehydrogenase/Aldh/1 |right|CAPTION=Human aldehyde hydrogenase class 2 complex with NAD , [[1nzx]] }}
'''Aldehyde dehydrogenase''' (ALDH) converts aldehydes to carboxylic acids while reducing NAD+ to NADH. In mammals there are 3 classes of ALDH and each contain constitutive and inducible forms. Class 1 is cytosolic; class 2 mitochondrial; class 3 found in tumors, stomach and cornea). ALDH family 7 member A1 is known as antiquitin and functions in the detoxification of aldehydes. Glyceraldehyde-3-phophate (G3P)-ALDH is called GAPDH.
'''Aldehyde dehydrogenase''' (ALDH) converts aldehydes to carboxylic acids while reducing NAD+ to NADH. In mammals there are 3 classes of ALDH and each contain constitutive and inducible forms. Class 1 is cytosolic; class 2 mitochondrial; class 3 found in tumors, stomach and cornea). ALDH family 7 member A1 is known as antiquitin and functions in the detoxification of aldehydes. Glyceraldehyde-3-phophate (G3P)-ALDH is called GAPDH.

Revision as of 10:28, 27 April 2011

Image:1nzx.png
Crystal Structure of Aldehyde dehydrogenase, 1nzx

Template:STRUCTURE 1nzx

Aldehyde dehydrogenase (ALDH) converts aldehydes to carboxylic acids while reducing NAD+ to NADH. In mammals there are 3 classes of ALDH and each contain constitutive and inducible forms. Class 1 is cytosolic; class 2 mitochondrial; class 3 found in tumors, stomach and cornea). ALDH family 7 member A1 is known as antiquitin and functions in the detoxification of aldehydes. Glyceraldehyde-3-phophate (G3P)-ALDH is called GAPDH.

Contents

3D Structures of Aldehyde dehydrogenase

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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