1a22

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{{Seed}}
 
[[Image:1a22.png|left|200px]]
[[Image:1a22.png|left|200px]]
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==About this Structure==
==About this Structure==
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1A22 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A22 OCA].
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[[1a22]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A22 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:9571026</ref><references group="xtra"/>
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<ref group="xtra">PMID:009571026</ref><ref group="xtra">PMID:012682073</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ultsch, M.]]
[[Category: Ultsch, M.]]
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[[Category: Hormone]]
[[Category: Hormone]]
[[Category: Pituitary]]
[[Category: Pituitary]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:19:12 2009''
 

Revision as of 13:00, 28 April 2011

Template:STRUCTURE 1a22

HUMAN GROWTH HORMONE BOUND TO SINGLE RECEPTOR

Template:ABSTRACT PUBMED 9571026

About this Structure

1a22 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Clackson T, Ultsch MH, Wells JA, de Vos AM. Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity. J Mol Biol. 1998 Apr 17;277(5):1111-28. PMID:9571026 doi:10.1006/jmbi.1998.1669
  • Duda KM, Brooks CL. Identification of residues outside the two binding sites that are critical for activation of the lactogenic activity of human growth hormone. J Biol Chem. 2003 Jun 20;278(25):22734-9. Epub 2003 Apr 7. PMID:12682073 doi:10.1074/jbc.M212550200

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