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3qiy

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[[Image:3qiy.jpg|left|200px]]
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==Reference==
==Reference==
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<ref group="xtra">PMID:21434688</ref><references group="xtra"/>
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<ref group="xtra">PMID:021434688</ref><references group="xtra"/>
[[Category: Bontoxilysin]]
[[Category: Bontoxilysin]]
[[Category: Clostridium botulinum]]
[[Category: Clostridium botulinum]]

Revision as of 05:58, 25 May 2011

Template:STRUCTURE 3qiy

Crystal Structure of BoNT/A LC complexed with Hydroxamate-based Inhibitor PT-1

Template:ABSTRACT PUBMED 21434688

About this Structure

3qiy is a 1 chain structure with sequence from Clostridium botulinum. Full crystallographic information is available from OCA.

Reference

  • Thompson AA, Jiao GS, Kim S, Thai A, Cregar-Hernandez L, Margosiak SA, Johnson AT, Han GW, O'Malley S, Stevens RC. Structural Characterization of Three Novel Hydroxamate-based Zinc Chelating Inhibitors of the C. botulinum Serotype A Neurotoxin Light Chain Metalloprotease Reveals a Compact Binding Site Resulting from 60/70 Loop Flexibility. Biochemistry. 2011 Mar 24. PMID:21434688 doi:10.1021/bi2001483

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