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3s2o
From Proteopedia
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| - | + | [[Image:3s2o.jpg|left|200px]] | |
| - | The | + | <!-- |
| + | The line below this paragraph, containing "STRUCTURE_3s2o", creates the "Structure Box" on the page. | ||
| + | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
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| + | {{STRUCTURE_3s2o| PDB=3s2o | SCENE= }} | ||
| - | + | ===Fragment based discovery and optimisation of bace-1 inhibitors=== | |
| - | + | ||
| + | <!-- | ||
| + | The line below this paragraph, {{ABSTRACT_PUBMED_20656487}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 20656487 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_20656487}} | ||
| + | |||
| + | ==About this Structure== | ||
| + | [[3s2o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3msm 3msm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S2O OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:020656487</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Memapsin 2]] | ||
| + | [[Category: Barker, J.]] | ||
| + | [[Category: Godemann, R.]] | ||
| + | [[Category: Hallett, D.]] | ||
| + | [[Category: Kraemer, J.]] | ||
| + | [[Category: Madden, J.]] | ||
| + | [[Category: Smith, M A.]] | ||
Revision as of 05:39, 1 June 2011
Fragment based discovery and optimisation of bace-1 inhibitors
Template:ABSTRACT PUBMED 20656487
About this Structure
3s2o is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3msm. Full crystallographic information is available from OCA.
Reference
- Madden J, Dod JR, Godemann R, Kraemer J, Smith M, Biniszkiewicz M, Hallett DJ, Barker J, Dyekjaer JD, Hesterkamp T. Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5329-33. Epub 2010 Jun 27. PMID:20656487 doi:10.1016/j.bmcl.2010.06.089
