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2xns
From Proteopedia
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| + | {{STRUCTURE_2xns| PDB=2xns | SCENE= }} | ||
| - | + | ===CRYSTAL STRUCTURE OF HUMAN G ALPHA I1 BOUND TO A DESIGNED HELICAL PEPTIDE DERIVED FROM THE GOLOCO MOTIF OF RGS14=== | |
| - | Description: Crystal Structure Of Human G alpha i1 Bound To A Designed Helical Peptide Derived From The Goloco Motif Of RGS14 | ||
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| + | The line below this paragraph, {{ABSTRACT_PUBMED_21388199}}, adds the Publication Abstract to the page | ||
| + | (as it appears on PubMed at http://www.pubmed.gov), where 21388199 is the PubMed ID number. | ||
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| + | {{ABSTRACT_PUBMED_21388199}} | ||
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| + | ==About this Structure== | ||
| + | [[2xns]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XNS OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:021388199</ref><ref group="xtra">PMID:017603074</ref><ref group="xtra">PMID:011976690</ref><references group="xtra"/> | ||
| + | [[Category: Heterotrimeric G-protein GTPase]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Bosch, D.]] | ||
| + | [[Category: Butterfoss, G L.]] | ||
| + | [[Category: Kuhlman, B.]] | ||
| + | [[Category: Machius, M.]] | ||
| + | [[Category: Sammond, D W.]] | ||
| + | [[Category: Siderovski, D P.]] | ||
Revision as of 05:09, 8 June 2011
CRYSTAL STRUCTURE OF HUMAN G ALPHA I1 BOUND TO A DESIGNED HELICAL PEPTIDE DERIVED FROM THE GOLOCO MOTIF OF RGS14
Template:ABSTRACT PUBMED 21388199
About this Structure
2xns is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sammond DW, Bosch DE, Butterfoss GL, Purbeck C, Machius M, Siderovski DP, Kuhlman B. Computational design of the sequence and structure of a protein-binding peptide. J Am Chem Soc. 2011 Mar 30;133(12):4190-2. Epub 2011 Mar 9. PMID:21388199 doi:10.1021/ja110296z
- Sammond DW, Eletr ZM, Purbeck C, Kimple RJ, Siderovski DP, Kuhlman B. Structure-based protocol for identifying mutations that enhance protein-protein binding affinities. J Mol Biol. 2007 Aug 31;371(5):1392-404. Epub 2007 Jun 8. PMID:17603074 doi:10.1016/j.jmb.2007.05.096
- Kimple RJ, Kimple ME, Betts L, Sondek J, Siderovski DP. Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits. Nature. 2002 Apr 25;416(6883):878-81. PMID:11976690 doi:http://dx.doi.org/10.1038/416878a
