This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2c41
From Proteopedia
(New page: 200px<br /> <applet load="2c41" size="450" color="white" frame="true" align="right" spinBox="true" caption="2c41, resolution 1.81Å" /> '''X-RAY STRUCTURE OF ...) |
|||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2C41 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Thermosynechococcus_elongatus Thermosynechococcus elongatus]] with CL, PG4 and PGE as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2C41 OCA]]. | + | 2C41 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Thermosynechococcus_elongatus Thermosynechococcus elongatus]] with CL, PG4 and PGE as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2C41 OCA]]. |
==Reference== | ==Reference== | ||
| Line 29: | Line 29: | ||
[[Category: thermostable protein]] | [[Category: thermostable protein]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:14:40 2007'' |
Revision as of 10:09, 30 October 2007
|
X-RAY STRUCTURE OF DPS FROM THERMOSYNECHOCOCCUS ELONGATUS
Overview
DNA-binding proteins from starved cells (Dps proteins) protect bacteria, primarily from oxidative damage. They are composed of 12 identical, subunits assembled with 23-symmetry to form a compact cage-like structure, known to be stable at temperatures > 70 degrees C and over a wide pH, range. Thermosynechococcus elongatus Dps thermostability is increased, dramatically relative to mesophilic Dps proteins. Hydrophobic interactions, at the dimeric and trimeric interfaces called Dps-like are replaced by, salt bridges and hydrogen bonds, a common strategy in thermophiles., Moreover, the buried surface area at the least-extended Dps-like interface, is significantly increased. A peculiarity of T. elongatus Dps is the, presence of a chloride ion coordinated with threefold symmetry-related, ... [(full description)]
About this Structure
2C41 is a [Single protein] structure of sequence from [Thermosynechococcus elongatus] with CL, PG4 and PGE as [ligands]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].
Reference
Antioxidant Dps protein from the thermophilic cyanobacterium Thermosynechococcus elongatus., Franceschini S, Ceci P, Alaleona F, Chiancone E, Ilari A, FEBS J. 2006 Nov;273(21):4913-28. Epub 2006 Oct 3. PMID:17018059
Page seeded by OCA on Tue Oct 30 12:14:40 2007
Categories: Single protein | Thermosynechococcus elongatus | Ceci, P. | Chiancone, E. | Franceschini, S. | Ilari, A. | CL | PG4 | PGE | Dna-binding protein | Dps (dna-binding proteins from starved cells) | Iron binding | Iron-binding/oxidation protein | Stress protein | Thermophilic cyanobacterium | Thermostable protein
