2c2m

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{{Seed}}
 
[[Image:2c2m.png|left|200px]]
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==About this Structure==
==About this Structure==
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2C2M is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C2M OCA].
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[[2c2m]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C2M OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:16970398</ref><references group="xtra"/>
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<ref group="xtra">PMID:016970398</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Asgian, J L.]]
[[Category: Asgian, J L.]]
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[[Category: Cpp32]]
[[Category: Cpp32]]
[[Category: Cysteine-protease]]
[[Category: Cysteine-protease]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Ice]]
[[Category: Ice]]
[[Category: Michael acceptor]]
[[Category: Michael acceptor]]
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[[Category: Tetramer]]
 
[[Category: Thiol protease]]
[[Category: Thiol protease]]
[[Category: Yama]]
[[Category: Yama]]
[[Category: Zymogen]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 03:42:25 2009''
 

Revision as of 07:02, 20 July 2011

Template:STRUCTURE 2c2m

CRYSTAL STRUCTURES OF CASPASE-3 IN COMPLEX WITH AZA-PEPTIDE MICHAEL ACCEPTOR INHIBITORS.

Template:ABSTRACT PUBMED 16970398

About this Structure

2c2m is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ekici OD, Li ZZ, Campbell AJ, James KE, Asgian JL, Mikolajczyk J, Salvesen GS, Ganesan R, Jelakovic S, Grutter MG, Powers JC. Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2, -3, -6, -7, -8, -9, and -10. J Med Chem. 2006 Sep 21;49(19):5728-49. PMID:16970398 doi:http://dx.doi.org/10.1021/jm0601405

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