1bck
From Proteopedia
(New page: 200px<br /> <applet load="1bck" size="450" color="white" frame="true" align="right" spinBox="true" caption="1bck, resolution 1.80Å" /> '''HUMAN CYCLOPHILIN A...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1BCK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BCK OCA]]. | + | 1BCK is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]]. Active as [[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8]]. Structure known Active Site: BIN. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1BCK OCA]]. |
==Reference== | ==Reference== | ||
X-ray structures and analysis of 11 cyclosporin derivatives complexed with cyclophilin A., Kallen J, Mikol V, Taylor P, Walkinshaw MD, J Mol Biol. 1998 Oct 23;283(2):435-49. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9769216 9769216] | X-ray structures and analysis of 11 cyclosporin derivatives complexed with cyclophilin A., Kallen J, Mikol V, Taylor P, Walkinshaw MD, J Mol Biol. 1998 Oct 23;283(2):435-49. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9769216 9769216] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| + | [[Category: Peptidylprolyl isomerase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Kallen, J.]] | [[Category: Kallen, J.]] | ||
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[[Category: complex (isomerase/immunosuppressant)]] | [[Category: complex (isomerase/immunosuppressant)]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 12:20:03 2007'' |
Revision as of 10:15, 30 October 2007
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HUMAN CYCLOPHILIN A COMPLEXED WITH 2-THR CYCLOSPORIN
Overview
Eight new X-ray structures of different cyclophilin, A/cyclosporin-derivative complexes are presented. These structures, combined with the existing three published cyclosporin complexes, provide, a useful structural database for the analysis of protein-ligand, interactions. The effect of small chemical differences on protein-ligand, hydrogen-bonding, van der Waals interactions and water structure is, presented.
About this Structure
1BCK is a [Single protein] structure of sequence from [Homo sapiens]. Active as [Peptidylprolyl isomerase], with EC number [5.2.1.8]. Structure known Active Site: BIN. Full crystallographic information is available from [OCA].
Reference
X-ray structures and analysis of 11 cyclosporin derivatives complexed with cyclophilin A., Kallen J, Mikol V, Taylor P, Walkinshaw MD, J Mol Biol. 1998 Oct 23;283(2):435-49. PMID:9769216
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