3srv

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'''Unreleased structure'''
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[[Image:3srv.jpg|left|200px]]
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The entry 3srv is ON HOLD until Paper Publication
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{{STRUCTURE_3srv| PDB=3srv | SCENE= }}
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Authors: Somers, D.O., Neu, M.
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===Crystal structure of spleen tyrosine kinase (SYK) in complex with a diaminopyrimidine carboxamide inhibitor===
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Description: Crystal structure of spleen tyrosine kinase (SYK) in complex with a diaminopyrimidine carboxamide inhibitor
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{{ABSTRACT_PUBMED_21903390}}
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==About this Structure==
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[[3srv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SRV OCA].
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==Reference==
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<ref group="xtra">PMID:021903390</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Non-specific protein-tyrosine kinase]]
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[[Category: Neu, M.]]
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[[Category: Somers, D O.]]
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[[Category: Non-receptor tyrosine kinase]]
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[[Category: Phosphorylation]]
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[[Category: Sk363]]
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[[Category: Spleen tyrosine kinase]]
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[[Category: Syk]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 05:53, 21 September 2011

Image:3srv.jpg

Template:STRUCTURE 3srv

Crystal structure of spleen tyrosine kinase (SYK) in complex with a diaminopyrimidine carboxamide inhibitor

Template:ABSTRACT PUBMED 21903390

About this Structure

3srv is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Liddle J, Atkinson FL, Barker MD, Carter PS, Curtis NR, Davis RP, Douault C, Dickson MC, Elwes D, Garton NS, Gray M, Hayhow TG, Hobbs CI, Jones E, Leach S, Leavens K, Lewis HD, McCleary S, Neu M, Patel VK, Preston AG, Ramirez-Molina C, Shipley TJ, Skone PA, Smithers N, Somers DO, Walker AL, Watson RJ, Weingarten GG. Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor. Bioorg Med Chem Lett. 2011 Aug 12. PMID:21903390 doi:10.1016/j.bmcl.2011.07.082

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OCA

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