DNA methyltransferase
From Proteopedia
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| + | {{STRUCTURE_1qnt|  PDB=1qnt  | SIZE=400| SCENE= |right|CAPTION=Human O6-methylguanine DNA methyltransferase, [[1qnt]] }} | ||
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| '''DNA methyltransferase''' (DNMT) catalyzes the transfer of methyl group to DNA.  DNMT uses S-adenosyl methionine (SAM) as the methyl donor.   | '''DNA methyltransferase''' (DNMT) catalyzes the transfer of methyl group to DNA.  DNMT uses S-adenosyl methionine (SAM) as the methyl donor.   | ||
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| + | == 3D Structures of DNA methyltransferase == | ||
| ===Methylguanine DNMT=== | ===Methylguanine DNMT=== | ||
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| [[1nw7]] - RsN6-adenine DNMT + S-adenonosyl cysteine | [[1nw7]] - RsN6-adenine DNMT + S-adenonosyl cysteine | ||
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| + | [[Category:Topic Page]] | ||
Revision as of 21:00, 29 September 2011
DNA methyltransferase (DNMT) catalyzes the transfer of methyl group to DNA. DNMT uses S-adenosyl methionine (SAM) as the methyl donor.
| Contents | 
3D Structures of DNA methyltransferase
Methylguanine DNMT
1sfe – O6-methylguanine DNMT C terminal – Escherichia coli
1qnt, 1eh6, 3llr - hO6-methylguanine DNMT – human
1t38 - hO6-methylguanine DNMT (mutant) + DNA
1t39, 1yfh - hO6-methylguanine DNMT + DNA
1eh7 - hO6-methylguanine DNMT methylated
1eh8 - hO6-methylguanine DNMT benzylated
1wrj - O6-methylguanine DNMT  - Sulfolobus tokodaii
2g7h - O6-methylguanine DNMT – Methanocaldococcus jannaschii
2kif, 2kim - O6-methylguanine DNMT – Vibrio parahaemolyticus - NMR
Methylcytosine DNMT
2qrv - h-cytosine DNMT
3epz - h-cytosine DNMT replecation foci-targeting sequence
3flg - h-cytosine DNMT ADD domain
3a1a - h-cytosine DNMT PWWP domain
3av4 - m-cytosine DNMT – mouse
2c7o, 2c7p, 2c7q, 2c7r, 3pta – Hh-cytosine DNMT + DNA + S-adenonosyl cysteine
2uyc, 2uyh, 2uz4 - Hh-cytosine DNMT (mutant) + DNA + S-adenonosyl cysteine
3a1b - h-cytosine DNMT ADD domain + histone H3
3pt6, 3pt9 – m-cytosine DNMT + DNA
3av5 - m-cytosine DNMT + S-adenonosyl cysteine
3av6 - m-cytosine DNMT + SAM
3swr - h-cytosine DNMT + sinefungin
1fjx – HhDNMT (mutant) + DNA + S-adenonosyl cysteine - Haemophilus haemolyticus
Methyladenine DNMT
1nw5 – RsN6-adenine DNMT + SAM – Rhodobacter sphaeroides
1nw6 - RsN6-adenine DNMT + sinefungin
1nw7 - RsN6-adenine DNMT + S-adenonosyl cysteine
