This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1qks
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:1qks.jpg|left|200px]]<br /><applet load="1qks" size=" | + | [[Image:1qks.jpg|left|200px]]<br /><applet load="1qks" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1qks, resolution 1.28Å" /> | caption="1qks, resolution 1.28Å" /> | ||
'''CYTOCHROME CD1 NITRITE REDUCTASE, OXIDISED FORM'''<br /> | '''CYTOCHROME CD1 NITRITE REDUCTASE, OXIDISED FORM'''<br /> | ||
| Line 7: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
| - | 1QKS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Paracoccus_denitrificans Paracoccus denitrificans] with SO4, HEC, DHE and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=C1A:The C Haem Is The Point Of Electron Entry'>C1A</scene>, <scene name='pdbsite=C1B:The C Haem Is The Point Of Electron Entry'>C1B</scene>, <scene name='pdbsite=D1A:The D1 Haem Is The Site Of Catalytic Acti'>D1A</scene> and <scene name='pdbsite=D1B:The D1 Haem Is The Site Of Catalytic Acti'>D1B</scene>. Full crystallographic information is available from [http:// | + | 1QKS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Paracoccus_denitrificans Paracoccus denitrificans] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=HEC:'>HEC</scene>, <scene name='pdbligand=DHE:'>DHE</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=C1A:The+C+Haem+Is+The+Point+Of+Electron+Entry'>C1A</scene>, <scene name='pdbsite=C1B:The+C+Haem+Is+The+Point+Of+Electron+Entry'>C1B</scene>, <scene name='pdbsite=D1A:The+D1+Haem+Is+The+Site+Of+Catalytic+Acti'>D1A</scene> and <scene name='pdbsite=D1B:The+D1+Haem+Is+The+Site+Of+Catalytic+Acti'>D1B</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QKS OCA]. |
==Reference== | ==Reference== | ||
| Line 25: | Line 25: | ||
[[Category: periplasmic]] | [[Category: periplasmic]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Feb 3 10:00:46 2008'' |
Revision as of 08:00, 3 February 2008
|
CYTOCHROME CD1 NITRITE REDUCTASE, OXIDISED FORM
Overview
Cytochrome cd1-nitrite reductase is a bifunctional enzyme that catalyzes, the one-electron reduction of nitrite to nitric oxide and the, four-electron reduction of oxygen to water. The 1.55 A crystal structure, of the dimeric enzyme from Thiosphaera pantotropha is reported here. The, protein was sequenced from the X-ray structure. Each subunit contains a, covalent c heme with two axial His ligands (His-17, His-69) and a unique, noncovalent d1 heme ligated by Tyr-25 and His-200. The d1 heme is the, mononuclear iron center where both oxygen and nitrite reduction take, place. The two types of heme are located in separate domains whose, arrangement suggests a mechanism requiring domain movement during, catalysis.
About this Structure
1QKS is a Single protein structure of sequence from Paracoccus denitrificans with , , and as ligands. Known structural/functional Sites: , , and . Full crystallographic information is available from OCA.
Reference
The anatomy of a bifunctional enzyme: structural basis for reduction of oxygen to water and synthesis of nitric oxide by cytochrome cd1., Fulop V, Moir JW, Ferguson SJ, Hajdu J, Cell. 1995 May 5;81(3):369-77. PMID:7736589
Page seeded by OCA on Sun Feb 3 10:00:46 2008
Categories: Paracoccus denitrificans | Single protein | Fulop, V. | DHE | GOL | HEC | SO4 | Denitrification | Electron transport | Enzyme | Nitrite reductase | Oxidoreductase | Periplasmic
